LSDA: Life Sciences Data Archive

Immunological Assessment of Crewmembers : DSO 487

Wed, 25 Nov 2009 05:52:46 GMT

OBJECTIVES:
The assessment of crew immunocompetence was required for the determination of space flight infectious disease risk. This is of significant importance for longer duration missions and particularly, orbital station environments.

Human Lymphocyte Locomotion in Microgravity : DSO 322

Wed, 25 Nov 2009 05:52:46 GMT
OBJECTIVES:
Understanding the movement of white blood cells (leukocytes) is a vital step for cancer researchers to determine how to help lemphocytes penetrate tissue to kill tumors. This is important because the lymphocytes fight cancers and all types of infection by moving into the diseased area. In the case of cancer, however; researchers have discovered that the closer a lymphocyte ...

Musculoskeletal Effects of 16-Weeks of Training with the advanced Resistive Exercise Device (aRED) : ROI_ARED

Wed, 25 Nov 2009 05:52:46 GMT
OBJECTIVES:
Resistive exercise has been recommended as a means to ease musculoskeletal de-conditioning due to spaceflight. Currently, the interim Resistive Exercise Device (iRED) is used on-board the International Space Station (ISS) as a method of providing resistive exercise. The iRED may not provide an adequate stimulus to bring about changes in muscle strength and mass and bone mineral d ...

Animal Enclosure Module Inflight Test : SSIP-8

Wed, 25 Nov 2009 05:52:46 GMT
Objectives:
The Animal Enclosure Module (AEM) was developed for an SSIP experiment flown on STS-41B. The purpose of this study was to test the ability of the AEM to maintain healthy rats in space with no dangers to crew safety, as this was the first time a cage of animals was flown in the crew compartment of the Shuttle. The major safety concerns involved microbial, particulate, and odo ...

Otolith Tilt-Translation Reinterpretation : DSO 459

Wed, 25 Nov 2009 05:52:46 GMT
OBJECTIVES:
The Otolith Tilt-Translation Reinterpretation hypothesized that adaptation to space flight is a function of sensory rearrangement and that signals from the otolith organs during orbital flight are reinterpreted as linear displacements.
An important question relating to this concept concerns the maintenance or substitution by other sensory systems of information to th ...

Animal Enclosure Module In-flight Test : DSO 421

Wed, 25 Nov 2009 05:52:46 GMT
OBJECTIVES:
This experiment was flown as a Detailed Supplementary Objective (DSO) to test the efficacy of the Animal Enclosure Module (AEM) in supporting healthy animals without compromising crew safety and comfort. This study represents the first attempt to fly animals in the crew compartment of a United States space vehicle, and ground testing was accordingly rigorous.
The AEM ...

Preflight and Postflight Parallel Swing Tests : DSO 433

Wed, 25 Nov 2009 05:52:46 GMT
This investigation obtained 5 subjects, including those obtained as part of DSO 449; DSO 433 was renamed to DSO 449 prior to the STS-51D flight.
Findings supported the Otolith Tilt-Translation Reinterpretation hypothesis. ...

Preflight and Postflight Parallel Swing Tests : DSO 449

Wed, 25 Nov 2009 05:52:46 GMT
OBJECTIVES:
An otolith is a structure in the inner ear, specifically in the vestibular labyrinth. They are sensitive to gravity and linear acceleration. The vestibular otolith receptors respond to linear motion and gravity. If motion cues from visual and skin receptors were reduced or eliminated, responses to roll and linear translation attributable primarily to the otolith receptors ...

Evaluation of Muscle Size Measurement with Ultrasound and Magnetic Resonance Imaging – Pilot Study : EORS_Ultrasound

Wed, 25 Nov 2009 05:52:46 GMT
OBJECTIVES:
Space flight crewmembers continue to experience muscle atrophy after space flight, particularly from long duration missions on the International Space Station (ISS), which results in higher risk for injury upon their return to Earth. More robust exercise equipment is arriving on the ISS and new exercise prescriptions are planned to counteract the muscle losses. With these new ex ...

Analysis of Skeletal Muscle Metrics as Predictors of Functional Task Performance : EORS_FOI

Wed, 25 Nov 2009 05:52:46 GMT
OBJECTIVES:
Space flight induces a host of physiological changes that have harmful effects on human function in normal gravity. Upon entry into a gravitational environment, astronauts must cope with impairments in strength, balance, and the ability to ambulate. Although scientific investigations have begun to explain the underlying physiological mechanisms of these changes; the corre ...